Come "Turkey Trot with DeCo" - Thanksgiving Morning, Nov 27th!

  • Home
  • Tickets / Donations
  • Walk with DeCo Mission
  • Humanized Mouse Model
  • Thank You
  • More
    • Home
    • Tickets / Donations
    • Walk with DeCo Mission
    • Humanized Mouse Model
    • Thank You
  • Sign In

  • My Account
  • Signed in as:

  • filler@godaddy.com


  • My Account
  • Sign out

Signed in as:

filler@godaddy.com

  • Home
  • Tickets / Donations
  • Walk with DeCo Mission
  • Humanized Mouse Model
  • Thank You

Account


  • My Account
  • Sign out


  • Sign In
  • My Account

Advancing VEDS Research Through A New Collaboration

A Humanized Mouse Model

As part of our mission to accelerate research on VEDS (Vascular Ehlers-Danlos Syndrome), we are excited to announce a new partnership with The Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. This effort brings an engineering perspective to the study of this rare and life-threatening collagen disorder.


Led by Dr. W. Robert Taylor and a dedicated team of faculty, researchers, and staff, this joint initiative aims to deepen scientific understanding of VEDS.


The First Step: A Humanized Mouse Model


The project’s initial focus is the development of a humanized mouse model using DNA from the national database. This model will be made available to the broader scientific community, benefiting not only VEDS research but also studies on other collagen disorders—broadening its impact and scientific value.


Next Steps in the Research


Two mouse lines will be generated: one with the VEDS mutation and one without (control). The VEDS-mutation model will undergo:


  • Histological analysis of vascular tissue
  • Protein production analysis
  • mRNA sequencing
  • Mechanical testing of aortic segments
  • Platelet function analysis


Ultimately, researchers will conduct challenge studies to test hypertensive agents, potential therapeutics, and age-related effects.


Timeline


This groundbreaking project is expected to take 20–24 months to complete.

Copyright © 2021 Walk with DeCo, Inc. - All Rights Reserved.

  • Privacy Policy
  • Terms and Conditions

Powered by

This website uses cookies.

We use cookies to analyze website traffic and optimize your website experience. By accepting our use of cookies, your data will be aggregated with all other user data.

Accept